In order to explore the causes of adhesion between rubber seal and metal flange and the influence of adhesion on sealing,according to the use characteristics of silicone rubber sealing structure,adhesion experiments between the silicon rubber sealing ring and the metal flange at different temperatures and times were designed.Through the comparative experiments of silicon rubber sealing ring with anti-rust aluminum alloy and two kinds of stainless steel materials,it is found that the silicone rubber sealing ring is prone to adhere to the stainless steel flange and is not prone to adhere to the anti-rust aluminum alloy metal flange.By testing the contact angle of metal flange surface,it is concluded that the greater the surface energy and the thinner the oxide layer,the easier the adhesion occurs.It is shown that the adhesion of silicone rubber seal ring in long-term contact with metal flange is caused by the existence of chemical bond between the interface,and this chemical reaction intensifies with the increase of time at a certain temperature.The results of mechanical analysis on sealing structure and sealing ring leakage test show that the static sealing performance of the sealing structure will not change whether adhesion occurs or not.