To study the effect of the coiled tubing wear on the sealing performance of the coiled tubing stripper, the common wear forms of the outer wall of coiled tubing were summarized,and the wear geometric models were constructed.Taking the coiled tubing stripper with diameter of 38.1 mm as an example,the constitutive model parameters of packer material were obtained through experiments,and the finite element model for sealing the coiled tubing with packer was established.Using the effective contact stress and maximum Mises stress as the evaluation indexes of sealing performance,the effects of the wear form,wear depth,wear length and off-wear angle on the sealing performance of the tube were analyzed.The results show that the off-wear forms of coiled tubing have great influence on the sealing performance of the packer,and when the length of coiled tubing off-wear section is larger than the height of the packer and the depth of the off-wear is greater than 1 mm,the sealing capacity of the packer cannot meet the wellhead sealing requirement.The off-wear angle will affect the stress distribution of the packer and thus affecting the sealing performance.