To investigate the Mises stress and contact pressure distribution of the sealing structure during the assembly process of the proton exchange membrane fuel cell,this paper selects the rectangular cross-section sealing gasket as the research object and establishes a 2D finite element model of the sealing structure of the proton exchange membrane fuel cell based on Abaqus software.The Mises stress and contact pressure distributions of the sealing structure are investigated under different compression rates,sealing gasket heights,fluid pressures,and assembly errors,and the effects on the performance of the sealing structure are explored according to the force conditions.The results show that the contact pressure of the sealing structure increases with the increase of compression rate,but the compression rate is too large to cause the failure of the sealing material; the height of the sealing gasket affects the magnitude of the contact pressure,and the contact pressure decreases with the increase of the height; the fluid pressure leads to the uneven force of the sealing structure,and the sealing gasket of the stressed side is subjected to a greater contact pressure; the assembling error causes the mechanical deformation of the membrane electrode frame,and the mechanical deformation of the membrane electrode frame increases with the increase of the error,and the contact pressure is increased with the increase of the error.Mechanical deformation,as the error increases,the Mises stress of the membrane electrode frame also increases gradually.