With the continuous development of high-temperature,high-pressure,H2S/CO2-containing oil and gas fields,the service environment of rubber materials for packers is becoming more and more severe.To study the adaptability of rubber sealing materials in high temperature and high pressure environments containing H2S/CO2,the stratum environment of Bozhong 19-6 block was simulated in an autoclave,and the corrosion resistance tests of four rubbers were carried out,including Fluorosilicone rubber(FVMQ),fluorocarbon rubber(FKM),hydrogenated nitrile rubber(HNBR) and tetrafluoroethylene-propylene elastomer(FERM).Electronic tensile testing machine and Shore hardness tester were used to test the cross-sectional micro-morphology,mechanical properties and hardness of the rubber material before and after exposure to the simulated environment.Experimental results show that the corrosion resistance of rubber in the simulated environment from high to low is HNBR,FEPM,FKM,FVMQ.HNBR has the most stable performance in the simulated working environment,which is due to the fact that the unsaturated bond of its molecules is used as a crosslinking point for vulcanization,which enhances its corrosion resistance to a certain extent.The mechanical properties of FEPM in the gas phase are reduced by about 75% compared with those in the liquid phase,and the presence of CO2 will aggravate the H2S corrosion of FEPM.FKM and FVMQ are seriously corroded and are not suitable for use in this simulated working condition.